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January 1975

Acne Detergicans

Arch Dermatol. 1975;111(1):65-68. doi:10.1001/archderm.1975.01630130067007

Popular brands of soaps and shampoos were assayed for comedogenicity in the rabbit ear. Only a small number produced hyperkeratosis when applied at a 25% concentration. Bacteriostatic substances, especially hexachlorophene, were mildly comedogenic. Conventional soaps include salts of fatty acids; the latter are known comedogens.

The obsessive use of soaps by patients with acne vulgaris may aggravate the disease and result in its extension to unusual locations.