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January 1975

Hemangioma-Thrombocytopenia Syndrome: A Disseminated Intravascular Coagulopathy

Author Affiliations

From the University of Michigan Medical Center, Ann Arbor, Mich. Dr. Lang is now in private practice in Columbia, SC.

Arch Dermatol. 1975;111(1):105-107. doi:10.1001/archderm.1975.01630130107016

A patient who had multiple hemangiomas and for whom results of coagulation studies were consistent with the hemangioma-thrombocytopenia (Kasabach-Merritt) syndrome and a microangiopathic hemolytic process was asymptomatic prior to surgical removal of a lipoma. Postoperatively, she developed bleeding secondary to a disseminated intravascular coagulopathy. Her bleeding was controlled by anticoagulation therapy. A review of the literature provides evidence suggesting that the hemangioma-thrombocytopenia syndrome is due to a disseminated intravascular coagulopathy initiated within the hemangioma. Surgical trauma may precipitate exacerbations of the coagulopathy in these patients and all unnecessary surgical procedures should be avoided.