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January 1975

HOUSTON DERMATOLOGICAL SOCIETY: Selected Case Presentations, 1972-1973

Arch Dermatol. 1975;111(1):120-122. doi:10.1001/archderm.1975.01630130122019

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Incontinentia Pigmenti. Presented by Donald W. Owens, MD.  An infant girl was the mother's first child. The mother had had no important medical illnesses. On the second day of life, the infant began having generalized seizures that subsided after treatment with diphenylhydantoin and phenobarbital. A lumbar puncture showed normal findings.The electroencephalogram was abnormal showing episodic build-ups of seizure activity in the right central region.When the patient was born, she had "spots" that were suggestive of erythema toxicum on the right hand and right arm. While still hospitalized, she began to develop additional skin lesions. Examination showed a linear vesicular eruption limited to the extremities. A skin biopsy specimen showed the changes of the acute phaseof incontinentia pigmenti, with spongiosis and eosinophilic infiltration.

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