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March 1975

Soft-Tissue Calcification in Systemic Lupus Erythematosus

Author Affiliations

From the Clinical Immunology and Rheumatic Disease Section, departments of medicine and pathology, Los Angeles County-University of Southern California Medical Center, Los Angeles.

Arch Dermatol. 1975;111(3):352-356. doi:10.1001/archderm.1975.01630150072008

Calcification of soft tissues is known to occur frequently in progressive systemic sclerosis (PSS) and dermatomyositis. To our knowledge, only seven case reports have appeared concerning this abnormality in systemic lupus erythematosus (SLE). We describe four patients with well-documented SLE who developed calcification in subcutaneous tissue, muscle, or periarticular structures. The pattern and localization of the calcification can mimic those seen in other disorders.