Lymphomatoid granulomatosis is a necrotizing arteritis primarily affecting the lungs but also found in the skin, kidneys, central nervous system, and other extrapulmonary sites. Cutaneous involvement occurred in 45% of the cases described by Liebow in his original series.
Light microscopy studies were performed. The IgA and IgG levels were slightly decreased and the IgE level was elevated. Cell-mediated immunity was impaired. No viruses were isolated or identified by immunofluorescence.
A man had cutaneous lesions as the first sign of lymphomatoid granulomatosis.
Minars N, Kay S, Escobar MR. Lymphomatoid Granulomatosis of the Skin: A New Clinicopathologic Entity. Arch Dermatol. 1975;111(4):493–496. doi:10.1001/archderm.1975.01630160083009
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