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July 1975

Macular Amyloidosis

Author Affiliations

Farmington, Mich

Arch Dermatol. 1975;111(7):929-930. doi:10.1001/archderm.1975.01630190119027

To the Editor. —  Macular amyloidosis is characterized by pruritic, macular pigmented patches that occur most commonly on the upper trunk, especially on the interscapular area.1 However it may also involve the thighs, shins, arms,2,3 buttocks, and rarely the face.4 Histologically, it is characterized by deposits of amyloid in the dermal papillae. It is a benign chronic condition, and except for reports by Shanon5 and Porto6 of its existence with atopy, neurodermatitis or vasomotor rhinitis and the unusual case of Black's7 in which a 53-year-old woman had systemic sclerosis and thickened plaques on the dorsum of the fingers, in which amyloid could be seen in the dermal papillae, there have been no reports of systemic disease associated with macular amyloidosis.I would like to report a case of macular amyloidosis associated with myelofibrosis with myeloid metaplasia.

Report of a Case.—  A 76-year-old woman was

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