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July 1975

Unusual Case of Granuloma Annulare

Author Affiliations



Arch Dermatol. 1975;111(7):931. doi:10.1001/archderm.1975.01630190121030

To the Editor.—  Granuloma annulare is not an uncommon clinical cutaneous disease. A hereditary predisposition to this disease has been suspected because of reported cases in twins or siblings that have occurred almost simultaneously.1,2 In a comprehensive review of this disease, Wells and Smith note that less than 5% of patients have facial lesions, and that cases occurring in siblings are not common.1 The case reported here is distinctive because of the appearance of unilateral multiple lesions on the face and the positive family history of the disease.This healthy 10-year-old boy had first noticed a 2-cm oval lesion with an indurated border on the dorsal aspect of the right hand 1½ years ago. Shortly thereafter, similar but smaller confluent lesions appeared on the right cheek, left forearm, and left hand. The lesions were oval patterns having a papular border and clear center. A biopsy specimen from the

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