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December 1975

Incontinentia Pigmenti and Defective Neutrophil Chemotaxis

Author Affiliations

From the departments of dermatology and pediatrics, Children's Hospital of San Francisco; University of California (San Francisco) Medical Center; and the Department of Medicine, the Permanente Medical Group, Kaiser-Permanente Medical Center, San Francisco. Dr Dahl is now at the University of Minnesota Medical Center, Minneapolis.

Arch Dermatol. 1975;111(12):1603-1605. doi:10.1001/archderm.1975.01630240059010

• A child with incontinentia pigmenti and chronic erythema multiforme had recurrent bacterial infections. Greatly elevated serum IgE was found. In addition, the patient's neutrophils showed essentially no chemotaxis toward Staphylococcus aureus, Escherichia coli, or Pseudomonas aeruginosa in either patient or control serum. Neutrophil phagocytosis and killing function were normal.

(Arch Dermatol 111:1603-1605, 1975)

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