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April 1976

Acne and Serum Androgens During Puberty

Author Affiliations


From the Clinical Investigation Center, Naval Regional Medical Center Oakland, Calif, and the Reproductive Endocrinology Program, Department of Pathology, University of Michigan, Ann Arbor. Dr Lee is now at Johns Hopkins Hospital, Baltimore.

Arch Dermatol. 1976;112(4):482-484. doi:10.1001/archderm.1976.01630280012003

• Mean concentrations of testosterone in sera collected from pubertal boys at the onset of acne were significantly higher than levels from stage-matched control pubertal boys who did not develop acne (P < .0025). This longitudinal study indicated that acne occurred when other androgen-produced pubertal changes began. Androstenedione and dehydroepiandrosterone levels did not differ between the two groups.

(Arch Dermatol 112:482-484, 1976)

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