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June 1976

Benign Chronic Bullous Dermatosis of Childhood: Linear IgA and C3 Deposition on the Basement Membrane

Author Affiliations


From the Department of Dermatology Research, Letterman Army Institute of Research, Presidio of San Francisco (Dr Prystowsky), and the Division of Dermatology, University of Texas Southwestern Medical School, Dallas (Dr Gilliam).

Arch Dermatol. 1976;112(6):837-838. doi:10.1001/archderm.1976.01630300045009

• Benign chronic bullous dermatosis of childhood (BCBDC) is characterized by predominantly monomorphous, large, tense bullae with a predilection for the lower part of the trunk, the pelvic region, and the lower extremities. Most patients have blisters for two to three years and experience spontaneous exacerbations and remissions. We report the first case known to us in which a linear band of IgA (but no IgG or IgM) and complement was found at the epidermal basal lamina as demonstrated by immunoflurorescence studies.

(Arch Dermatol 112:837-838, 1976)