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June 1976

Methoxsalen and Irradiation: Treatment for Pustulosis Palmaris et Plantaris

Arch Dermatol. 1976;112(6):883-884. doi:10.1001/archderm.1976.01630300079025

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To the Editor.—  Treatment of pustulosis palmaris et plantaris frequently presents a most difficult problem. We have found that the topical or systemic administration of methoxsalen (8-MOP), followed by long-wave ultraviolet light irradiation, is effective in this disease.

Materials and Methods.—  Two hours after each patient received a single oral dose of 40 mg of methoxsalen, the lesions were irradiated with fluorescent black light tubes that emitted from 300 to 430 nm, with the maximum at 352 nm. The irradiance at 352 ± 5 nm was 1.6 milliwatts/sq cm · 10 nm. The light dose was adjusted to the erythema and edema response, which occurred at about 20 to 60 minutes ofCASE 1. CASE 2. CASE 3. FEET CASE 4. RIGHT FOOT 4 6 NUMBER OF TREATMENTS 12 14

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