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August 1976

Pemphigus Foliaceus: Early Clinical Appearance as Dermatitis Herpetiformis With Eosinopholic Spongiosis

Author Affiliations


From the Department of Dermatology, University of North Carolina, Chapel Hill. Dr Osteen is now with the US Air Force Hospital, Langley Air Force Base, Va, and Dr Puritz is now in private practice in Smithtown, NY.

Arch Dermatol. 1976;112(8):1148-1152. doi:10.1001/archderm.1976.01630320054017

• We encountered an unusual case of pemphigus foliaceus in which there were early clinical signs of dermatitis herpetiformis with eosinophilic spongiosis histologically. Numerous authors have appreciated that eosinophilic spongiosis occurs in early pemphigus foliaceus, usually in the preacantholytic stage when the lesions may clinically simulate dermatitis herpetiformis. Recognition of eosinophilic spongiosis may help differentiate early pemphigus from other vesiculobullous disorders.

(Arch Dermatol 112:1148-1152, 1976)