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August 1976

Chemotherapy for Kaposi Sarcoma

Arch Dermatol. 1976;112(8):1179. doi:10.1001/archderm.1976.01630320077033

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To the Editor.—  I read with great interest the article "Chemotherapy for Advanced Kaposi Sarcoma" in the Archives (111:1331-1333, 1975) by Lanzotti et al. It was a well-written article that detailed combination chemotherapy of advanced Kaposi sarcoma. However, the authors stated that their case represented "the first verified response of visceral Kaposi sarcoma to chemotherapy reported in the literature." I should like to point out that I reported two patients in 1974 (Chest 66:522-525) who responded to chemotherapy with intravenously administered vinblastine. One patient had marked pulmonary infiltrates and the other had pericardial involvement. While treatment was only palliative, both patients still experienced a marked regression of their disease with chemotherapy.Internal involvement in non-African Kaposi sarcoma is being recognized with increasing frequency, and experience with chemotherapy has been limited in this advanced stage of the disease.Successful combination chemotherapy for internal involvement in Kaposi sarcoma as described by

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