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August 1976

Treatment of Plantar Warts With Bleomycin

Arch Dermatol. 1976;112(8):1179. doi:10.1001/archderm.1976.01630320077035

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To the Editor.—  New methods for the treatment of warts appear from time to time. Thus, it is not surprising that another is available. For the past year, I have been injecting bleomycin sulfate (Blenoxane) into recurrent or recalcitrant plantar warts with great success.One always hesitates to herald the use of anything in the treatment of warts with any more than casual enthusiasm. However, as a trial, it was decided to treat with the bleomycin sulfate only those plantar warts that (1) were of twelve (or more) months' duration; (2) had been treated with any of the common methods but that had recurred; (3) were grouped together, forming a mosaic pattern (ie, were mosaic warts); and (4) occurred on patients who were more than 12 years old. Twenty-five patients had plantar warts that satisfied these criteria. After a six-month follow-up period, only three of the patients showed evidence

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