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September 1976

Cutaneous Extramedullary Hematopoiesis: Report of a Case

Author Affiliations

From the Department of Pathology, Division of Surgical Pathology (Dr Kuo), the Department of Dermatology (Dr Uhlemann), and the Department of Medicine (Dr Reinhard), Washington University School of Medicine and Barnes Hospital, St Louis.

Arch Dermatol. 1976;112(9):1302-1303. doi:10.1001/archderm.1976.01630330064018

• An asymptomatic skin nodule in a patient with myelofibrosis was shown to consist of extramedullary hematopoiesis. It was a soft bluish nodule that resembled a hemangioma. Microscopically, both erythroid and myeloid cells, but not megakaryocytes, were found. This case demonstrates the ability of the skin to recapitulate dermal hematopoiesis seen in a stage of human fetal development.

(Arch Dermatol 112:1302-1303, 1976)