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September 1976

Clindamycin Therapy for Moderately Severe Acne

Author Affiliations

Newport Beach, Calif

Arch Dermatol. 1976;112(9):1323. doi:10.1001/archderm.1976.01630330077026

To the Editor.—  I was surprised to read at this late date an article advocating the use of clindamycin in the treatment of "moderately severe acne" in the Archives (111:997, 1975). With all the warnings from the Food and Drug Administration and from the Upjohn Company itself, and with all the publicity regarding its dangerous side effects in the medical press, it certainly seems obvious that clindamycin should not be used in a condition that is not life-threatening, such as acne.In the last two paragraphs of their article, Christian and Krueger do make note of some of the serious side effects and say that "until such side effects are understood, judicious use is indicated." Judicious use, it seems, would dictate that it should not be used in the treatment of acne at all.Granted that clindamycin is effective in treating acne, I would maintain that with 45 deaths from