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October 1976

Vesicular Pemphigoid

Author Affiliations

From the departments of dermatology, Baylor College of Medicine, Houston (Drs Bean and Meltzer), Case Western Reserve University School of Medicine, Cleveland (Dr Michel), Northwestern University Medical School, Chicago (Dr Furey), and University of Colorado Medical School, Denver (Dr Thorne).

Arch Dermatol. 1976;112(10):1402-1404. doi:10.1001/archderm.1976.01630340020005

† Seven patients had a chronic eruption of small vesicles that was initially considered to be atypical dermatitis herpetiformis. Histopathologic studies disclosed a subepidermal bulla that was compatible with either bullous pemphigoid or dermatitis herpetiformis. Immunofluorescence studies demonstrated deposition of IgG or C3, or both, at the basement-membrane zone (BMZ) in six of seven patients. In four patients, circulating BMZ antibodies were detected also. We believe that these cases represent a vesicular form of bullous pemphigoid.

(Arch Dermatol 112:1402-1404, 1976)