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November 1976

Lichen Planus and Bullous Pemphigoid

Author Affiliations

Fort Dix, NJ

Arch Dermatol. 1976;112(11):1613. doi:10.1001/archderm.1976.01630350079026

To the Editor.—  In a recent article in the British Journal of Dermatology,1 a patient was described with both lichen planus and bullous pemphigoid. To my knowledge, no similar cases have been presented in the American literature. We are now following up a 64-year-old black woman who was first seen in early July 1975 with a one month's history of a pruritic eruption involving the trunk, back, extremities, and oral mucosa. The clinical and histological diagnosis was lichen planus. In late July, bullae developed on the previously involved skin. Biopsy of the bullous lesion was diagnostic of bullous lichen planus. The patient's serum at that time was positive for circulating antibasement membrane antibody in a 1:80 titer. Subsequently, a biopsy was performed from a bulla, and tissue-fixed antibasement zone antibody was also demonstrated. Results of studies for antinuclear antibody and antiepithelial cell antibody were normal.The patient has been