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July 1977

Permanent Anonychia After Stevens-Johnson Syndrome

Author Affiliations

From the Department of Dermatology, Rigs-hospital, Copenhagen.

Arch Dermatol. 1977;113(7):970. doi:10.1001/archderm.1977.01640070104018

Loss of nails with scarring that leads to anonychia may occur on a congenital basis, as in the nail-patella syndrome and the dystrophic epidermolysis bullosa, or on an acquired basis, as seen after severe trauma, as well as in the case of impaired peripheral circulation, in lichen planus, and in bullous drug eruptions.1 Any drugs that induce bullae can cause nail changes or nail loss due to destruction of the nail matrix.1

To our knowledge, hitherto nothing has been written about the nail changes in Stevens-Johnson syndrome. Therefore, we will present such a case report of a patient with permanent nail loss.

Report of a Case  A 29-year-old man was admitted to the dermatology department April through July 1971 with a fulminant attack of Stevens-Johnson syndrome.Physical examination results showed suppurative conjunctivitis on both eyes and edema and redness of the eyelids. On the lips and around the

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