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July 1977

Transient Acantholytic Dermatosis in South Africa

Arch Dermatol. 1977;113(7):982. doi:10.1001/archderm.1977.01640070116023

To the Editor.—  A fair-haired, 63-year-old man, whose occupation was a builder, had had an intensely itching rash on his back of two months' duration. His work caused him to be in the sun for much of the day, and he also had many actinic keratoses on his face and arms.On examination, he had a red, maculopapular rash on the back that resembled pityriasis rosea. The rash was slightly scaly. The individual lesions, however, seemed unusually firm. At the time, I was convinced of the diagnosis of pityriasis rosea and did a skin biopsy. The histologic characteristics showed hyperkeratosis with focal parakeratosis. The epidermis also showed suprabasal clefts and vesicles. Within the vesicles there were shrunken, distorted acantholytic cells. There were no corps ronds. As a result of the clinical history and the histologic findings, a diagnosis of transient acantholytic dermatosis was made. The following blood values were obtained:

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