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August 1977

Simultaneous Occurrence of Goodpasture's Syndrome and Follicular Mucinosis

Arch Dermatol. 1977;113(8):1129. doi:10.1001/archderm.1977.01640080131030

To the Editor.—  Both Goodpasture's syndrome and follicular mucinosis are uncommon or even rare conditions, both of obscure cause. We recently had the opportunity to study a patient with both conditions.

Report of a Case.—  In July 1974, a 12-year-old girl developed hemoptysis and subsequently hematuria. She was hospitalized and thoroughly examined, and the diagnosis of Goodpasture's syndrome was confirmed by characteristic routine and immunofluorescence findings on lung and renal biopsy specimens, as well as by positive circulating antiglomerular basement membrane antibodies. She was treated with high doses of prednisone (60 to 100 mg daily), azathioprine (Imuran) (100 mg daily), as well as methyldopa (Aldomet), hydralazine hydrochloride, furosemide (Lasix), and potassium chloride. She did well, except for seizures due to hypertensive encephalopathy, and her prednisone was gradually tapered. In December, she developed a follicular eruption on her forehead and cheeks, which was believed to be steroid acne. This was treated

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