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August 1977

Familial Localized Scleroderma (Morphoea)

Author Affiliations

Peshawar, Pakistan

Arch Dermatol. 1977;113(8):1132-1133. doi:10.1001/archderm.1977.01640080134038

To the Editor.—  Familial scleroderma is a rare condition; to our knowledge, only nine documented instances of the disease have been reported. This report adds one more family to the literature. Four children, three brothers and one sister, had clinically and histologically established localized scleroderma.In 1953, Rees and Bennett1 reported the first documented instance of localized scleroderma occurring in two members of the same family. In 1968, Burge and Perry2 after reviewing the literature on familial scleroderma presented four more documented instances. In 1972, Szczepanski and Jakubowicz3 reported another instance of localized scleroderma in two sisters. In 1975, Wuthrich et al4 reported another two instances of localized scleroderma.

Report of Cases.—Case 1.—  In November 1975 a 15-year-old boy with morphoea involving all four limbs was examined. The lesions had started to develop 11 years previously and gradually increased in size. During the winter,

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