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September 1977

Mycophenolic Acid for Psoriasis

Author Affiliations

From the Cleveland Clinic Foundation.

Arch Dermatol. 1977;113(9):1203-1208. doi:10.1001/archderm.1977.01640090051004

• Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A doubleblind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P < .01). A long-term safety study showed the occurrence of hematologic abnormalities, viral infections, and carcinoma. The position of mycophenolic acid in the therapeutic treatment of psoriasis must await the results of a multicenter cooperative study.

(Arch Dermatol 113:1203-1208, 1977)

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