The experience of Dr Unger represents, for most of us, a compelling argument for the use of steroids in the treatment of alopecia areata. All of us have observed individual patients who have responded nicely to this form of therapy and who apparently have remained in remission after therapy has been discontinued. Despite the relatively small number of patients we have described, the validity of our report, as with any scientific study, must be assessed by statistical analysis of the entire population. Such an analysis of our population revealed no apparent improvement in the long-term course of alopecia areata with prednisone therapy. Clearly, individuals within this population, as Dr Unger indicates, are at variance with this conclusion. We wish there were some way of identifying those who would benefit from such therapy and those who would not.Several of Dr Unger's comments concerning side effects in our patients
Winter RJ, Kern F, Blizzard RM. Prednisone Therapy for Alopecia Areata-Reply. Arch Dermatol. 1977;113(10):1457. doi:10.1001/archderm.1977.01640100135033
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