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November 1977

Ocular Involvement in Pyoderma Gangrenosum

Author Affiliations

Münster, West Germany

Arch Dermatol. 1977;113(11):1612. doi:10.1001/archderm.1977.01640110132035

To the Editor.—  Pyoderma gangrenosum (PG) is an inflammatory disease of unknown origin that may be associated with ulcerative colitis and polyarthritis.1-3 Ocular involvement, however, has not been reported to our knowledge. We observed a patient with PG of the left temporal region and ipsilateral ulcerative scleritis.

Report of a Case.—  A 64-year-old man had had seronegative asymmetrical arthritis of the distal finger joints, the knees, and the sacroiliacal joints for many years. There was no evidence of rheumatic nodules, bowel disease, or a hematological disorder. In 1971, several inflammatory papules appeared on his left temple. Ulceration of these lesions resulted in a 6 × 10-cm defect with a highly inflamed margin (Fig 1). Simultaneously, severe scleral conjunctivitis of the left eye occurred and was followed by a scleral ulcer, anterior uveitis, and corneal opacity (Fig 2). Histological examination of biopsy specimens from both ocular and cutaneous lesions revealed

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