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November 1977

Griseofulvin Therapy in Molluscum Contagiosum

Arch Dermatol. 1977;113(11):1615. doi:10.1001/archderm.1977.01640110135048

To the Editor.—  Griseofulvin has recently been found useful in the treatment of viral warts (unpublished data) and molluscum contagiosum.1 Keeping this in mind, we treated five cases of extensive molluscum contagiosum with griseofulvin fine particles, giving dosages of 500 mg a day, orally, for patients above 14 years of age, and half this dosage for younger patients. The treatment was continued for four to six weeks. The patients ranged in age from 4 to 17 years and had had lesions for 15 to 30 days. In each patient, the lesions started to regress within two weeks after treatment was begun, and the lesions completely disappeared in four to six weeks. There had been no recurrence of the condition in any of these patients after six to eight months of follow-up.Although further studies are required to attribute antiviral activity to griseofulvin, disappearance of the lesions in every case

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