• A patient had a unique mechanobullous disease (Bart's syndrome). The characteristic congenital localized skin defects, trauma-induced erosions, and nail deformities are present. The inheritance pattern appears to be autosomal dominant but, as in this report, isolated cases have been recognized.
In a review of the other mechanobullous diseases, Bart's syndrome appears to present a distinctive clinical picture and course and has a favorable prognosis. The progressive spontaneous improvement emphasizes the importance of early recognition and conservative treatment.
(Arch Dermatol 114:81-84, 1978)
Smith SZ, Cram DL. A Mechanobullous Disease of the Newborn: Bart's Syndrome. Arch Dermatol. 1978;114(1):81–84. doi:10.1001/archderm.1978.01640130045013
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