Dr Olsen questions the specificity of the lupus band test (LBT) taken from clinically normal skin as a diagnostic tool. He cites a recent abstract by Baldassare et al1 (published after the submission of my review article), who found deposits of IgM at the dermal-epidermal junction in eight of 16 patients with rheumatoid arthritis. In my review article, I concluded that "the specificity of the LBT is very high in differentiating LE from other cutaneous disorders that are clinically similar."2 A review of the literature produces only isolated reports of positive LBTs in other disorders. A recent large series of studies by Burnham and Fine,3 Grossman et al,4 Gilliam,5 and Tuffanelli6 show that the LBT is positive in a very small percentage of cases of other ANA-positive diseases. By combining these four series, the frequency of positive LBTs in other ANA-positive diseases
Monroe EW. Lupus Band Test-Reply. Arch Dermatol. 1978;114(1):126–127. doi:10.1001/archderm.1978.01640130084033
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: