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February 1978

Graft-vs-Host Reaction

Author Affiliations

Scottsdale, Ariz

Arch Dermatol. 1978;114(2):289. doi:10.1001/archderm.1978.01640140097035

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To the Editor.—  I must take exception to the statement that Grogan and Odom make in their article titled "Graft-vs-Host Reaction" in the Archives (113:806-812, 1977). They state: "We now prefer the term 'satellite cell necrosis' (SCN), as it is both descriptively accurate and concise."Although it may be concise, I do not think that this term is an accurate description of the pathological process in the graft-vs-host reaction. One unfamiliar with this unique histopathological picture would envision necrosis of satellite cells in interpreting the term SCN. Furthermore, this term does not really furnish any information about just what these "necrotic satellites" are revolving around, causing the reader himself to turn in circles of confusion."Focal cellular necrosis with lymphocytic satellitosis" would be a more accurate description of the histopathological pattern seen in the acute graft-vs-host reaction. We must try to say just what we mean in medicine, especially in

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