• Reticular pigmented anomaly of the flexures (Dowling-Degos' anomaly) is a rare, benign, new genodermatosis that has recently evolved from independent observations and studies by several dermatologists. Because of its favorable prognosis, differentiation of this benign disorder from acanthosis nigricans, a cutaneous marker of possible or existing internal malignant disease, is highly important. Careful clinical appraisal of the eruption in correlation with the characteristic microscopic features makes the diagnosis simple and straightforward.
(Arch Dermatol 114:400-403, 1978)
Howell JB, Freeman RG. Reticular Pigmented Anomaly of the Flexures. Arch Dermatol. 1978;114(3):400–403. doi:10.1001/archderm.1978.01640150036011
Browse and subscribe to JAMA Network podcasts!
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: