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March 1978

Primary Adenoid Cystic Carcinoma of Skin

Author Affiliations

From the Departments of Pathology (Drs Headington and Teears), Dermatology (Dr Headington), and General Surgery (Dr Niederhuber), University of Michigan Medical Center, Ann Arbor. Dr Slinger is now with St Joseph's Hospital, London, Ontario.

Arch Dermatol. 1978;114(3):421-424. doi:10.1001/archderm.1978.01640150057018

• Two primary adenoid cystic carcinomas of skin were studied histologically and histochemically. Histologically, they closely resemble adenoid cystic carcinoma found in other tissues but in the skin must be distinguised from aggressive basal cell carcinomas. The natural history of these tumors and of those collected from the literature suggest a long indolent and progressive course. Local excision with meticulous histologic control of the surgical margins appears to be an appropriate therapeutic strategy. Thus far lymph node metastases have not been observed.

(Arch Dermatol 114:421-424, 1978)