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March 1978


Author Affiliations

From the Department of Dermatology, University of Louisville School of Medicine, Kentucky.

Arch Dermatol. 1978;114(3):458-459. doi:10.1001/archderm.1978.01640150086031

Despite the withdrawal of bromide from the prescription pharmacopoeia, some proprietary products contain substantial amounts of bromide salts.1 Therefore, potentially toxic amounts of bromide are readily available over the counter. We report this case of bromoderma to emphasize the presence of bromide in the pharmacopoeia and the importance of surveillance for its clinical presentation.

Report of a Case  A 41-year-old woman had a six-month history of an erythematous pustular eruption that involved primarily the lower legs. The thighs, upper extremities, and face were less affected. Four months after the onset of this eruption, larger bullous lesions that were filled with purulent material developed. Some of these lesions subsequently developed deep crater, ecthymatiform ulcers. In the month prior to seeking medical attention, strikingly large vegetative (fungoid) plaques with elevated papillomatous borders developed (Fig 1).The central portion of the plaques on her legs was studded with small pustules. Slight pressure