• The four male patients with multiple hamartoma syndrome (Cowden's disease) in this report, have most of the previously reported findings associated with this syndrome and several important unreported findings that include multiple cutaneous trichilemmomas, cafe-au-lait spots, cutaneous squamous cell carcinoma, pathologic fracture, craniomegaly, probable malignant lung tumor, retinal glioma, drusens of the optic disk and retina, pseudotumor cerebri, mediastinal mass, and multiple small papillomatous lesions of the esophagus, stomach, and duodenum.
(Arch Dermatol 114:743-746, 1978)
Nuss DD, Aeling JL, Clemons DE, Weber WN. Multiple Hamartoma Syndrome (Cowden's Disease). Arch Dermatol. 1978;114(5):743–746. doi:10.1001/archderm.1978.01640170043008
Browse and subscribe to JAMA Network podcasts!
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: