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May 1978

Resistant Condylomata Acuminata in Diabetics

Arch Dermatol. 1978;114(5):800. doi:10.1001/archderm.1978.01640170094035

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To the Editor.—  Condylomata acuminata are verrucous lesions of varying sizes that usually occur in the genital or anal area, and, rarely, in the axillae. During the past 18 months, 14 women between the ages of 19 and 46 years have sought therapy for recalcitrant genital condylomata of 8 to 14 months' duration. In all cases, coexisting insulin-dependent diabetes mellitus was present. All of the affected women had received varying concentrations of podophyllum resin in tincture of benzoin or alcoholic bases with poor results. A cryosurgical approach was instituted. In only 50% of these cases was it possible to achieve complete clearing, and this response was accomplished only after three months of biweekly treatments. Also, I am fully aware that spontaneous involution may have played a role in the cases that responded. I would be interested in finding out whether other practitioners examined diabetic women with unusually resistant genital

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