Chondroid syringoma is a cutaneous mixed tumor of salivary-gland-type usually located in the head and neck region. It usually has a prominent chondroid component. Hirsch and Helwig1 and Stout and Gorman2 have reported the largest series of cases, 188 and 134 respectively. Aggressive or frankly malignant behavior is rare and has been observed in only five instances.1,3-6 The presence of satellite nodules adjacent to the main mass and of cellular atypism and mitotic activity has been used as criterion of malignancy.
Report of a Case
A 15-year-old girl had a nodule in her left external auditory meatus that was excised but recurred three years later. She is now 21 years old and has no evidence of residual disease. Histologically, both the original lesion and the recurrence showed features of a chondroid syringoma (Fig 1, left and right), except for a moderate degree of pleomorphism and occasional mitoses
Botha JBC, Kahn LB. Aggressive Chondroid Syringoma: Report of a Case in an Unusual Location and With Local Recurrence. Arch Dermatol. 1978;114(6):954–955. doi:10.1001/archderm.1978.01640180086024
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