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June 1978

Treatment of Psoriasis With Dialysis

Author Affiliations

Columbia, Mo

Arch Dermatol. 1978;114(6):966. doi:10.1001/archderm.1978.01640180096039

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To the Editor.—  With Dr Karl Nolph, our director of nephrology, I have been observing two patients with very extensive, disabling psoriasis that had persisted without improvement for many years despite treatment with repeated trials of Goeckerman therapy and folic acid antagonists. These patients, who have no renal disease, were the first to undertake dialysis for psoriasis, and both have enjoyed prompt and total healing of the skin, which has been sustained without further treatment since April 1977. These initial cases were managed by Dr Nolph's renal fellow, Dr Z. J. Twardowski, who, I believe, is the first physician to perform dialysis specifically for psoriasis.At the University of Missouri Medical Center, Columbia, we are evaluating cases of psoriasis for dialysis and will continue preliminary evaluations of efficacy, particularly in regard to the possible benefit for early and severe, psoriatic arthritis. The exact treatment of the first three patients who

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