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September 1978

Scleroderma, Eosinophilia, and Diffuse Fasciitis

Author Affiliations

From the Divisions of Dermatology, Hahnemann Medical College and Hospital, Philadelphia (Drs Fleischmajer, Shore, and Binnick), and Hospital Henri Mondor, Creteil, France (Dr Jacotot).

Arch Dermatol. 1978;114(9):1320-1325. doi:10.1001/archderm.1978.01640210015004

• Skin induration without internal organ involvement, blood and tissue eosinophilia, and fasciitis are features of diffuse fasciitis. However, cellular infiltrates (lymphocytes, plasma cells, and eosinophils) may also be present in the dermis, fat, and muscle. Blood eosinophilia (mild and transient) and skin eosinophilia were observed in about 20% of patients with systemic and localized scleroderma.

(Arch Dermatol 114:1320-1325, 1978)