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September 1978

Multiple Periorbital Fibrous Histiocytomas: A Light and Electron Microscopic Study

Author Affiliations

From the Departments of Ophthalmology (Dr Tso) and Pathology (Dr Ronan), Abraham Lincoln School of Medicine, University of Illinois Hospital, Chicago.

Arch Dermatol. 1978;114(9):1345-1347. doi:10.1001/archderm.1978.01640210040011

• Recurrent, bilateral, multiple, periorbital fibrous histiocytomas occurred in a 62-year-old woman. There were no associated serum lipid abnormalities. Histologically, the tumor was composed of an admixture of lipid-laden histiocytes and fibroblasts with a variable amount of collagen production. In many areas the fibroblasts were arranged in a storiform pattern. No cytologic evidence of malignancy was observed. Ultrastructural studies of the tumor showed histiocytic cells with a variable amount of lipid in the cytoplasm and fibroblasts with mild to moderate collagen production. Differential diagnosis and histogenesis are discussed.

(Arch Dermatol 114:1345-1347, 1978)