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September 1978

Vitiligo, Chronic Thrombocytopenia, and Autoimmune Hemolytic Anemia

Author Affiliations

From the Department of Pediatrics, Division of Hematology-Oncology, New Jersey Medical School, Newark (Dr Walters), and the Department of Dermatology, Yale University School of Medicine, New Haven, Conn (Drs Lerner and Nordlund).

Arch Dermatol. 1978;114(9):1366-1367. doi:10.1001/archderm.1978.01640210061019

• A 12-year-old boy with vitiligo, chronic thrombocytopenia, and a Coombs's positive autoimmune hemolytic anemia was treated with oral psoralens and exposure to ultraviolet light. An acute hemolytic crisis developed and he died. The association of autoimmune hemolytic anemia and vitiligo should be looked for in other cases. Until more information is available, patients with vitiligo and thrombocytopenia should not be treated with psoralens and exposure to ultraviolet light.

(Arch Dermatol 114:1366-1367, 1978)