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November 1978

Endometrial Adenocarcinoma Metastatic to the Scalp

Author Affiliations

From the Department of Dermatology, Johns Hopkins Hospital, Baltimore.

Arch Dermatol. 1978;114(11):1708-1709. doi:10.1001/archderm.1978.01640230080023

Cutaneous metastasis from endometrial adenocarcinoma is an unusual occurrence. Our purpose is to report a case of endometrial adenocarcinoma in which metastasis was first documented by findings from a scalp biopsy. In addition, we have reviewed the experience at the Johns Hopkins Hospital with cutaneous metastasis from the uterus.

Report of a Case  A 53-year-old primiparous woman noticed vaginal bleeding in July 1977, six years after her menopause. Dilation and curettage demonstrated adenocarcinoma of the endometrium. A total abdominal hysterectomy was performed in August 1977, and no evidence of metastasis was found. Pathological examination showed tumor invasion halfway through the thickness of the myometrium.The patient was admitted to Johns Hopkins Hospital in September 1977 for pelvic irradiation. A thorough workup failed to document evidence of internal metastasis. Results of blood counts, blood chemistry studies, using an automated multiple analysis system, chest x-ray film with tomography, intravenous pyelography, cystoscopy, sigmoidoscopy,

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