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December 1978

Generalized Pustular Psoriasis Precipitated by Lithium Carbonate

Author Affiliations

From the Section of Dermatology, University of Wisconsin, Madison. Dr Lowe is now with the Division of Dermatology, UCLA School of Medicine, Los Angeles.

Arch Dermatol. 1978;114(12):1788-1789. doi:10.1001/archderm.1978.01640240030009

• Precipitation of generalized pustular psoriasis was manifested in a patient with previously stable psoriasis vulgaris following lithium carbonate therapy for manic-depressive psychosis. Methotrexate toxicity was observed during the acute stage of the illness, and photochemotherapy was the successful treatment. Further pustulation occurred when lithium carbonate therapy was reintroduced.

(Arch Dermatol 114:1788-1789, 1978)