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January 1979

Systemic Lupus Erythematosus and Dermatitis Herpetiformis: Concurrence With Marfan's Syndrome

Author Affiliations

From the Departments of Pediatrics (Drs A. J. Aronson and Ong) and Medicine (Drs Soltani and I. K. Aronson), the University of Chicago Pritzker School of Medicine and La Rabida Children's Hospital and Research Center, Chicago.

Arch Dermatol. 1979;115(1):68-70. doi:10.1001/archderm.1979.04010010040011

There is increasing evidence that, as in systemic lupus erythematosus (SLE), deposition of immune complexes plays a role in the pathogenesis of dermatitis herpetiformis (DH). Dermatitis herpetiformis and SLE were diagnosed in a 15-year-old girl with Marfan's syndrome who died of cardiac tamponade secondary to cystic medial necrosis of the ascending aorta. The concurrence of these diseases suggests that predisposition to immune-mediated disorders may be associated with the expression of multiple clinical entities.

(Arch Dermatol 115:68-70, 1979)

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