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January 1979

Hyperkeratosis of the Nipple

Author Affiliations

Guayaquil, Ecuador

Arch Dermatol. 1979;115(1):111. doi:10.1001/archderm.1979.04010010077043

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To the Editor.—  In the December 1977 issue of the Archives (113:1691-1692), Mehregan and Rahbari described two cases of hyperkeratosis of the nipple and areola of the nevoid type, and they mentioned that this is a very rare condition and, with their cases, there are only 15 reported cases in the literature.The following case was recently observed at the Dermatology, Venereology, and Allergy Unit, Ecuadorian Institute of Social Security, Guayaquil, Ecuador.

Report of a Case.—  A 21-year-old woman was seen in June 1978 for skin changes, involving both nipples, of five years' duration. Physical examination showed thickening of the nipples, with yellowish discoloration. The lesions were bilaterally symmetric and asymptomatic. Since March 1978, she had been receiving treatment with topical corticosteroids, topical tretinoin (retinoic acid), and oral vitamin A, without any progress. On physical examination, nevus sebaceus in the scalp and dystrophy of the teeth were found.This case

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