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February 1979

Bowen's Disease and Squamous Cell Carcinoma: Occurrence in a Patient With Psoriasis After Topical, Systemic, and PUVA Therapy

Author Affiliations

From the Department of Dermatology, Skin and Cancer Hospital, Temple University School of Medicine, Philadelphia.

Arch Dermatol. 1979;115(2):203-204. doi:10.1001/archderm.1979.04010020049015

Multiple lesions of Bowen's disease and squamous cell carcinoma on the penis and pubic areas developed in a 32-year-old patient with psoriasis who was undergoing treatment with psoralen and long-wave ultraviolet radiation (PUVA). A cumulative dose of more than 3,700 joules/sq cm of UVA had been administered over a three-year period. This case may be an early warning of possible carcinogenicity of PUVA therapy, alone or as part of sequential therapy with other agents.

(Arch Dermatol 115:203-204, 1979)

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