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February 1979

Photo-onycholysis and Psoralen Use-Reply

Author Affiliations

Columbus, Ohio

Arch Dermatol. 1979;115(2):235. doi:10.1001/archderm.1979.04010020069027

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In Reply.—  Many thanks to Dr Zala and colleagues for pointing out their excellent article "Photo-Onycholysis Induced by 8-Methoxypsoralen." As they may well have guessed, our letter was submitted to the Archives before their article was published.I was interested to read that their case 1 apparently was protected from photo-onycholysis by the use of dark nail polish. Despite my warnings, our patient continues to use methoxsalen (Oxsoralen) to achieve a tan. She has routinely used a dark nail polish for protection since her bout of photoonycholysis, and she has had no further trouble.I am not surprised that others have observed photo-onycholysis secondary to psoralen use. This may well be a relatively common occurrence.

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