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March 1979

Chronic Mucocutaneous Candidiasis: Successful Treatment With Intermittent Oral Doses of Clotrimazole

Author Affiliations

From the Department of Dermatology, Boston University School of Medicine.

Arch Dermatol. 1979;115(3):322-323. doi:10.1001/archderm.1979.04010030030011

Treatment of chronic mucocutaneous candidiasis has included drugs, immunotherapy, and replacement of nutritional and endocrine deficiency. Although amphotericin B is the best known and most commonly used form of treatment, the imidazole antibiotic clotrimazole has shown promise as an effective agent that can be given orally with low toxicity. A 9-year-old girl responded to intermittent clotrimazole therapy with complete and prolonged remission. This form of treatment offers advantages in safety and effectiveness over other therapies for chronic mucocutaneous candidiasis.

(Arch Dermatol 115:322-323, 1979)

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