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April 1979

Amelanotic Lentigo Maligna

Author Affiliations

From the Department of Dermatology, University of Oregon Health Sciences Center, Portland.

Arch Dermatol. 1979;115(4):496. doi:10.1001/archderm.1979.04010040074022

Tt is usual for lentigo maligna to present a variegated pigmented macule in which the degree of coloration and configuration are continually changing.1 I report a case in which an erythematous macule developed into an amelanotic melanoma.

Report of a Case  A 66-year-old woman was seen in 1977 because of a ten-year history of an erythematous lesion on the left side of the neck. It enlarged over the years to cover a 3 × 4-cm area. Two 0.75-cm nodules developed in the center of the lesion one year prior to examination.Thirteen years prior to examination, the patient had a lesion excised from the same area of the neck; histologic examination showed a pigmented compound nevus.On examination, the area surrounding the nodules was macular, erythematous, and amelanotic with indistinct borders (Fig 1). A punch biopsy specimen was obtained from the anterior aspect of the macule, and shave biopsy

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