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May 1979

Juvenile Dermatitis Herpetiformis: Immunopathology and HLA Typing

Author Affiliations

From the Department of Dermatology, University of Michigan, Ann Arbor.

Arch Dermatol. 1979;115(5):584-586. doi:10.1001/archderm.1979.04010050018007

Juvenile dermatitis herpetiformis occurred in a 20-month-old girl. She had granular IgA, C3, and fibrin bound to the basement membrane zone of the skin by direct immunofluorescence and negative serum antibodies against the skin on indirect immunofluorescence. The HLA typing of peripheral lymphocytes was A1, Aw30, B8, Bw51 without clinical evidence of malabsorption syndrome. A rapid improvement was observed on dapsone therapy. These findings strongly suggest that juvenile dermatitis hepetiformis is a disease entity different from chronic bullous dermatosis of childhood.

(Arch Dermatol 115:584-586, 1979)

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