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May 1979

Chronic Urticaria and Gallbladder Disease: Clearing After Cholecystectomy

Arch Dermatol. 1979;115(5):638. doi:10.1001/archderm.1979.04010050062033

To the Editor.—  Chronic urticaria is a difficult dermatologic problem of diverse causes. Although severe persistent urticaria demands thorough investigation, no causal factors are demonstrable in over 70% of patients.1,2 Herein is described a patient whose hives failed to clear until a diseased gallbladder was removed.

Report of a Case.—  A 30-year-old woman had had hives for one month at age 8. The next episode occurred in June 1975, when intermittent hives developed and their frequency increased to a daily occurrence by November 1975. An extensive evaluation at another hospital demonstrated no cause for her urticaria, and in February 1976, her symptoms abruptly cleared.In June 1976, the patient was first seen in the dermatology clinic of the US Army Hospital, Augsberg, Germany. She described progressively severe urticaria on arising that tended to clear during the day. The patient related that "acid" foods made her hives worse, and ingestion

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