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June 1979

Loeffler's Syndrome?-Reply

Author Affiliations



Presidio of San Francisco, Calif

Arch Dermatol. 1979;115(6):677-678. doi:10.1001/archderm.1979.04010060003011

In Reply.—  We wish to thank Dr Fine for his comments on our case report. Loeffler's syndrome as defined by various authors is a condition where symptoms are mild, transient pulmonary infiltrations are found, and a blood eosinophilia is present.1,2 When symptoms are present, cough is the most common; there is often no sputum production.1 Other symptoms that have been reported include malaise, headache, upper respiratory catarrh, hay fever, night sweats, chest pain, and angioneurotic edema.1 Fever is rare but has been reported to 3 °C.1 Crofton et al1 note that while roentgenographic changes usually disappear in six to 12 days, they may remain up to one month. Peripheral eosinophilia is usually in the range of 20%, but patients have been reported with as high as 70% eosinophils with a total WBC count of 12,900/cu mm.1The patients we described are regular joggers. On